abstract：BACKGROUND:Advances in genome technology have simplified a new comprehension of the genetic and historical processes crucial to rapid phenotypic evolution under domestication. To get new insight into the genetic basis of the dog domestication process, we conducted whole-genome sequence analysis of three wolves and thre...

journal_title：BMC genomics

authors： Amiri Ghanatsaman Z,Wang GD,Asadollahpour Nanaei H,Asadi Fozi M,Peng MS,Esmailizadeh A,Zhang YP

更新日期：2020-03-04 00:00:00

abstract：BACKGROUND:Diversification on the basis of utilization is a hallmark of Beta vulgaris (beet), as well as other crop species. Often, crop improvement and management activities are segregated by crop type, thus preserving unique genome diversity and organization. Full interfertility is typically retained in crosses betwe...

journal_title：BMC genomics

authors： Galewski P,McGrath JM

更新日期：2020-03-02 00:00:00

abstract：BACKGROUND:Matricaria recutita (German chamomile) and Chamaemelum nobile (Roman chamomile) belong to the botanical family Asteraceae. These two herbs are not only morphologically distinguishable, but their secondary metabolites - especially the essential oils present in flowers are also different, especially the terpen...

journal_title：BMC genomics

authors： Tai Y,Hou X,Liu C,Sun J,Guo C,Su L,Jiang W,Ling C,Wang C,Wang H,Pan G,Si X,Yuan Y

更新日期：2020-02-18 00:00:00

abstract：BACKGROUND:Climate plays an essential role in forest health, and climate change may increase forest productivity losses due to abiotic and biotic stress. Increased temperature leads to the increased formation of ozone (O3). Ozone is formed by the interaction of sunlight, molecular oxygen and by the reactions of chemica...

journal_title：BMC genomics

authors： Soltani N,Best T,Grace D,Nelms C,Shumaker K,Romero-Severson J,Moses D,Schuster S,Staton M,Carlson J,Gwinn K

更新日期：2020-02-14 00:00:00

abstract：BACKGROUND:Haplotypes combine the effects of several single nucleotide polymorphisms (SNPs) with high linkage disequilibrium, which benefit the genome-wide association analysis (GWAS). In the haplotype association analysis, both haplotype alleles and blocks are tested. Haplotype alleles can be inferred with the same st...

journal_title：BMC genomics

authors： Chen H,Hao Z,Zhao Y,Yang R

更新日期：2020-02-11 00:00:00

abstract：:After publication of [1], the authors were informed by John A. Rhodes of a counterexample to Theorem 11 of [1]. ...

journal_title：BMC genomics

authors： Nute M,Chou J,Molloy EK,Warnow T

更新日期：2020-02-10 00:00:00

abstract：BACKGROUND:Genome-scale pooled CRISPR screens are powerful tools for identifying genetic dependencies across varied cellular processes. The vast majority of CRISPR screens reported to date have focused exclusively on the perturbation of protein-coding gene function. However, protein-coding genes comprise < 2% of the se...

journal_title：BMC genomics

authors： Borys SM,Younger ST

更新日期：2020-01-31 00:00:00

abstract：BACKGROUND:Repetitive DNA is a major component of plant genomes and is thought to be a driver of evolutionary novelty. Describing variation in repeat content among individuals and between populations is key to elucidating the evolutionary significance of repetitive DNA. However, the cost of producing references genomes...

journal_title：BMC genomics

authors： Renny-Byfield S,Baumgarten A

更新日期：2020-01-30 00:00:00

abstract：BACKGROUND:Next generation sequencing (NGS) has become a universal practice in modern molecular biology. As the throughput of sequencing experiments increases, the preparation of conventional multiplexed libraries becomes more labor intensive. Conventional library preparation typically requires quality control (QC) tes...

journal_title：BMC genomics

authors： Chiniquy J,Garber ME,Mukhopadhyay A,Hillson NJ

更新日期：2020-01-28 00:00:00

abstract：BACKGROUND:Calcium-dependent protein kinase (CPK) is one of the main Ca2+ combined protein kinase that play significant roles in plant growth, development and response to multiple stresses. Despite an important member of the stress responsive gene family, little is known about the evolutionary history and expression pa...

journal_title：BMC genomics

authors： Zhang M,Liu Y,He Q,Chai M,Huang Y,Chen F,Wang X,Liu Y,Cai H,Qin Y

更新日期：2020-01-23 00:00:00

abstract：BACKGROUND:Gene targeting by homology-directed repair (HDR) can precisely edit the genome and is a versatile tool for biomedical research. However, the efficiency of HDR-based modification is still low in many model organisms including zebrafish. Recently, long single-stranded DNA (lssDNA) molecules have been developed...

journal_title：BMC genomics

authors： Bai H,Liu L,An K,Lu X,Harrison M,Zhao Y,Yan R,Lu Z,Li S,Lin S,Liang F,Qin W

更新日期：2020-01-21 00:00:00

abstract：BACKGROUND:Candida albicans is an opportunistic pathogenic yeast, which could become pathogenic in various stressful environmental factors including the spaceflight environment. In this study, we aim to explore the phenotypic changes and possible mechanisms of C. albicans after exposure to spaceflight conditions. RESU...

journal_title：BMC genomics

authors： Wang J,Liu Y,Zhao G,Gao J,Liu J,Wu X,Xu C,Li Y

更新日期：2020-01-17 00:00:00

abstract：BACKGROUND:Increasing evidence has shown that circular RNAs (circRNAs) are involved in neurodegenerative disorders, but their roles in neurological toxoplasmosis are yet to know. This study examined miRNA and circRNA expressions in mouse brain following oral infection with T. gondii Pru strain. RESULTS:Total RNA extra...

journal_title：BMC genomics

authors： Zhou CX,Ai K,Huang CQ,Guo JJ,Cong H,He SY,Zhu XQ

更新日期：2020-01-14 00:00:00

abstract：BACKGROUND:Health traits are of significant economic importance to the dairy industry due to their effects on milk production and associated treatment costs. Genome-wide association studies (GWAS) provide a means to identify associated genomic variants and thus reveal insights into the genetic architecture of complex t...

journal_title：BMC genomics

authors： Freebern E,Santos DJA,Fang L,Jiang J,Parker Gaddis KL,Liu GE,VanRaden PM,Maltecca C,Cole JB,Ma L

更新日期：2020-01-13 00:00:00

abstract：BACKGROUND:Decapods are an order of crustaceans which includes shrimps, crabs, lobsters and crayfish. They occur worldwide and are of great scientific interest as well as being of ecological and economic importance in fisheries and aquaculture. However, our knowledge of their biology mainly comes from the group which i...

journal_title：BMC genomics

authors： Nong W,Chai ZYH,Jiang X,Qin J,Ma KY,Chan KM,Chan TF,Chow BKC,Kwan HS,Wong CKC,Qiu JW,Hui JHL,Chu KH

更新日期：2020-01-09 00:00:00

abstract：BACKGROUND:The domestic cat (Felis catus) is an important companion animal and is used as a large animal model for human disease. However, the comprehensive study of adaptive immunity in this species is hampered by the lack of data on lymphocyte antigen receptor genes and usage. The objectives of this study were to ann...

journal_title：BMC genomics

authors： Radtanakatikanon A,Keller SM,Darzentas N,Moore PF,Folch G,Nguefack Ngoune V,Lefranc MP,Vernau W

更新日期：2020-01-06 00:00:00

abstract：:Following the publication of the original article [1], the authors reported an error in Fig. 2 of the PDF version of their article. ...

journal_title：BMC genomics

authors： Maarsingh JD,Yang S,Park JG,Haydel SE

更新日期：2019-12-31 00:00:00

abstract：BACKGROUND:Europeans and American Indians were major genetic ancestry of Hispanics in the U.S. These ancestral groups have markedly different incidence rates and outcomes in many types of cancers. Therefore, the genetic admixture may cause biased genetic association study with cancer susceptibility variants specificall...

journal_title：BMC genomics

authors： Wang LJ,Zhang CW,Su SC,Chen HH,Chiu YC,Lai Z,Bouamar H,Ramirez AG,Cigarroa FG,Sun LZ,Chen Y

更新日期：2019-12-30 00:00:00

abstract：BACKGROUND:Inadvertent sample swaps are a real threat to data quality in any medium to large scale omics studies. While matches between samples from the same individual can in principle be identified from a few well characterized single nucleotide polymorphisms (SNPs), omics data types often only provide low to moderat...

journal_title：BMC genomics

authors： Westphal M,Frankhouser D,Sonzone C,Shields PG,Yan P,Bundschuh R

更新日期：2019-12-30 00:00:00

abstract：BACKGROUND:Infectious disease outbreaks form major setbacks to aquaculture production and to further development of this important sector. Cyprinid herpes virus-3 (CyHV-3) is a dsDNA virus widely hampering production of common carp (Cyprinus carpio), one of the most farmed fish species worldwide. Genetically disease re...

journal_title：BMC genomics

authors： Tadmor-Levi R,Doron-Faigenboim A,Marcos-Hadad E,Petit J,Hulata G,Forlenza M,Wiegertjes GF,David L

更新日期：2019-12-26 00:00:00

abstract：BACKGROUND:Tandem mass spectrometry allows biologists to identify and quantify protein samples in the form of digested peptide sequences. When performing peptide identification, spectral library search is more sensitive than traditional database search but is limited to peptides that have been previously identified. An...

journal_title：BMC genomics

authors： Lin YM,Chen CT,Chang JM

更新日期：2019-12-24 00:00:00

abstract：BACKGROUND:Genetic resistance in cattle is considered a suitable way to control tick burden and its consequent losses for livestock production. Exploring tick-resistant (R) and tick-susceptible (S) hosts, we investigated the genetic mechanisms underlying the variation of Braford resistance to tick infestation. Skin bio...

journal_title：BMC genomics

authors： Moré DD,Cardoso FF,Mudadu MA,Malagó-Jr W,Gulias-Gomes CC,Sollero BP,Ibelli AMG,Coutinho LL,Regitano LCA

更新日期：2019-12-19 00:00:00

abstract：BACKGROUND:Phenomics provides new technologies and platforms as a systematic phenome-genome approach. However, few studies have reported on the systematic mining of shared genetics among clinical biochemical indices based on phenomics methods, especially in China. This study aimed to apply phenomics to systematically e...

journal_title：BMC genomics

authors： Hu Y,Tan A,Yu L,Hou C,Kuang H,Wu Q,Su J,Zhou Q,Zhu Y,Zhang C,Wei W,Li L,Li W,Huang Y,Huang H,Xie X,Lu T,Zhang H,Yang X,Gao Y,Li T,Jiang Y,Mo Z

更新日期：2019-12-16 00:00:00

abstract：BACKGROUND:The compromised performance of laying hens in the late phase of production relative to the peak production was thought to be associated with the impairment of intestinal functionality, which plays essential roles in contributing to their overall health and production performance. In the present study, RNA se...

journal_title：BMC genomics

authors： Wang WW,Wang J,Zhang HJ,Wu SG,Qi GH

更新日期：2019-12-12 00:00:00

abstract：BACKGROUND:Citrus blight is a very important progressive decline disease of commercial citrus. The etiology is unknown, although the disease can be transmitted by root grafts, suggesting a viral etiology. Diagnosis is made by demonstrating physical blockage of xylem cells that prevents the movement of water. This test ...

journal_title：BMC genomics

authors： Fu S,Shao J,Roy A,Brlansky RH,Zhou C,Hartung JS

更新日期：2019-12-11 00:00:00

abstract：BACKGROUND:Single nucleotide polymorphisms (SNPs) and insertions/deletions (InDels) are the major genetic variations and are distributed extensively across the whole plant genome. However, few studies of these variations have been conducted in the long-lived perennial tea plant. RESULTS:In this study, we investigated ...

journal_title：BMC genomics

authors： Liu S,An Y,Tong W,Qin X,Samarina L,Guo R,Xia X,Wei C

更新日期：2019-12-05 00:00:00

abstract：BACKGROUND:Gene expression variation is a key underlying factor influencing phenotypic variation, and can occur via cis- or trans-regulation. To understand the role of cis- and trans-regulatory variation on population divergence in chicken, we developed reciprocal crosses of two chicken breeds, White Leghorn and Cornis...

journal_title：BMC genomics

authors： Wang Q,Jia Y,Wang Y,Jiang Z,Zhou X,Zhang Z,Nie C,Li J,Yang N,Qu L

更新日期：2019-12-05 00:00:00

abstract：BACKGROUND:Malaria pathogenesis relies on sexual gametocyte forms of the malaria parasite to be transmitted between the infected human and the mosquito host but the molecular mechanisms controlling gametocytogenesis remains poorly understood. Here we provide a high-resolution transcriptome of Plasmodium falciparum as i...

journal_title：BMC genomics

authors： van Biljon R,van Wyk R,Painter HJ,Orchard L,Reader J,Niemand J,Llinás M,Birkholtz LM

更新日期：2019-12-03 00:00:00

abstract：BACKGROUND:The astounding regenerative abilities of planarian flatworms prompt steadily growing interest in examining their molecular foundation. Planarian regeneration was found to require hundreds of genes and is hence a complex process. Thus, RNA interference followed by transcriptome-wide gene expression analysis b...

journal_title：BMC genomics

authors： Kim IV,Ross EJ,Dietrich S,Döring K,Sánchez Alvarado A,Kuhn CD

更新日期：2019-11-29 00:00:00

abstract：BACKGROUND:Meloidogyne chitwoodi commonly known as Columbia root-knot nematode or CRKN is one of the most devastating pests of potato in the Pacific Northwest of the United States of America. In addition to the roots, it infects potato tubers causing internal as well as external defects, thereby reducing the market val...

journal_title：BMC genomics

authors： Bali S,Vining K,Gleason C,Majtahedi H,Brown CR,Sathuvalli V

更新日期：2019-11-28 00:00:00

abstract：BACKGROUND:Recent research has revealed that polymorphic behavioral strategies shape intra-and interspecific interactions and contribute to fitness in many animal species. A better understanding of the proximate mechanisms underlying these behavioral syndromes will enhance our grasp this phenomenon. Spiders in the genu...

journal_title：BMC genomics

authors： Purcell J,Pruitt JN

更新日期：2019-11-22 00:00:00

abstract：BACKGROUND:Nutritional quality of phytoplankton is a major determinant of the trophic transfer efficiency at the plant-herbivore interface in freshwater food webs. In particular, the phytoplankton's content of the essential polyunsaturated omega-3 fatty acid eicosapentaenoic acid (EPA) has been repeatedly shown to limi...

journal_title：BMC genomics

authors： Windisch HS,Fink P

更新日期：2019-11-21 00:00:00

abstract：BACKGROUND:Cadmium (Cd) is a serious heavy metal (HM) soil pollutant. To alleviate or even eliminate HM pollution in soil, environmental-friendly methods are applied. One is that special plants are cultivated to absorb the HM in the contaminated soil. As an excellent economical plant with ornamental value and sound ada...

journal_title：BMC genomics

authors： Wang MQ,Bai ZY,Xiao YF,Li Y,Liu QL,Zhang L,Pan YZ,Jiang BB,Zhang F

更新日期：2019-11-20 00:00:00

abstract：BACKGROUND:Intramuscular fat (IMF) is one of the most important factors positively associated with meat quality. Triglycerides (TGs), as the main component of IMF, play an essential role in muscle lipid metabolism. This transcriptome analysis of pectoralis muscle tissue aimed to identify functional genes and biological...

journal_title：BMC genomics

authors： Liu L,Liu X,Cui H,Liu R,Zhao G,Wen J

更新日期：2019-11-15 00:00:00

abstract：BACKGROUND:Endogenous α-synuclein (α-Syn) is involved in many pathophysiological processes in the secondary injury stage after acute spinal cord injury (SCI), and the mechanism governing these functions has not been thoroughly elucidated to date. This research aims to characterize the effect of α-Syn knockdown on trans...

journal_title：BMC genomics

authors： Zeng H,Yu BF,Liu N,Yang YY,Xing HY,Liu XX,Zhou MW

更新日期：2019-11-14 00:00:00

abstract：BACKGROUND:Cultivated peanut (Arachis hypogaea L.) is an important oil and protein crop, but it has low disease resistance; therefore, it is important to reveal the number, sequence features, function, and evolution of genes that confer resistance. Nucleotide-binding site-leucine-rich repeats (NBS-LRRs) are resistance ...

journal_title：BMC genomics

authors： Song H,Guo Z,Hu X,Qian L,Miao F,Zhang X,Chen J

更新日期：2019-11-13 00:00:00

abstract：BACKGROUND:At sexual maturity, the liver of laying hens undergoes many metabolic changes to support vitellogenesis. In published transcriptomic approaches, hundreds of genes were reported to be overexpressed in laying hens and functional gene annotation using gene ontology tools have essentially revealed an enrichment ...

journal_title：BMC genomics

authors： Gloux A,Duclos MJ,Brionne A,Bourin M,Nys Y,Réhault-Godbert S

更新日期：2019-11-07 00:00:00

abstract：BACKGROUND:Xanthomonas citri pv. citri (Xcc) is a citrus canker causing Gram-negative bacteria. Currently, little is known about the biological and molecular responses of Xcc to low temperatures. RESULTS:Results depicted that low temperature significantly reduced growth and increased biofilm formation and unsaturated ...

journal_title：BMC genomics

authors： Liao JX,Li KH,Wang JP,Deng JR,Liu QG,Chang CQ

更新日期：2019-11-06 00:00:00

abstract：BACKGROUND:Transmissible gastroenteritis virus (TGEV) infection can cause acute inflammation. Long noncoding RNAs (lncRNAs) play important roles in a number of biological process including inflammation response. However, whether lncRNAs participate in TGEV-induced inflammation in porcine intestinal epithelial cells (IP...

journal_title：BMC genomics

authors： Ma X,Zhao X,Wang K,Tang X,Guo J,Mi M,Qi Y,Chang L,Huang Y,Tong D

更新日期：2019-11-04 00:00:00

abstract：BACKGROUND:The hepatitis E virus (HEV) is the causative pathogen of hepatitis E, a global public health concern. HEV comprises 8 genotypes with a wide host range and geographic distribution. This study aims to determine the genetic factors influencing the molecular adaptive changes of HEV open reading frames (ORFs) and...

journal_title：BMC genomics

authors： Baha S,Behloul N,Liu Z,Wei W,Shi R,Meng J

更新日期：2019-10-29 00:00:00